Author

C. Daly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Plouffe· 3 shared A. Inoue· 2 shared A. R. B. Thomsen· 2 shared H. Hahn· 2 shared A. A. Guseinov· 1 shared A. K. Shukla· 1 shared A. Wright· 1 shared B. Khanppnavar· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCell Biology

B. Plouffe

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Author profile →

3 papers

Recent·Most cited

Structure of the human Duffy antigen receptor

S. Saha, B. Khanppnavar, J. Maharana, H. Kim, C. M. C. Carino, C. Daly, S. Houston, P. Kumari, P. N. Yadav, B. Plouffe, A. Inoue, K. Y. Chung, R. Banerjee, V. M. Korkhov, A. K. Shukla

This study determines the cryo-EM structure of the Duffy antigen receptor bound to CCL7, revealing structural features that explain its unique functional properties and lack of G protein coupling.

bioRxiv · Jul 9, 2023 · PreprintBiochemistry

β-arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor

C. Daly, A. A. Guseinov, H. Hahn, A. Wright, I. Tikhonova, A. R. B. Thomsen, B. Plouffe

This study shows the vasopressin type 2 receptor can activate G proteins at endosomes both with and without beta-arrestin, challenging existing models of GPCR signaling.

bioRxiv · Apr 1, 2023Cell Biology

Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration

H. Hahn, C. Daly, J. Little, N. A. Perry-Hauser, E. Flores-Espinoza, A. Inoue, B. Plouffe, A. R. B. Thomsen

This study shows endosomal chemokine receptor signaling, specifically through CCR7, enhances Rac1 activity and immune T cell chemotaxis by recruiting G protein and β-arrestin.

bioRxiv · Sep 27, 2022Cell Biology