Cell BiologybioRxivPreprint
LRRK2 kinase dependent and independent function on endolysosomal repair promotes macrophage cell death
R. Morrison, S. R. G. Mihaylov, C. H. Luk…·M. G. Gutierrez
This study identifies LRRK2-G2019S-dependent lysosomal membrane repair defects in macrophages leading to increased cell death.