Author

N. Bernhardt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Ecology· 1 Evolutionary Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:DNA methylation· 2 Approach:mechanistic / dynamical model· 2 Organism:plant (other)· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Assay:whole-genome sequencing· 2 Approach:Bayesian inference· 1

Frequent Co-Authors

J. Brassac· 2 shared J. Faraldo-Gomez· 2 shared J. L. Robertson· 2 shared R. Chadda· 2 shared T. N. Ozturk· 2 shared A. Forsythe· 1 shared A. Gil-Ley· 1 shared A. Tagiri· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersEvolutionary Biology

J. Brassac

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Author profile →

6 papers

Recent·Most cited

Distinct mechanisms of inhibition of Kv2 potassium channels by tetraethylammonium and RY785

S. Zhang, R. Stix, E. A. Orabi, N. Bernhardt, J. D. Faraldo-Gomez

This paper uses molecular dynamics simulations to compare how RY785 and TEA inhibit Kv2.1 channels, showing RY785 stabilizes a semi-open gate state while TEA blocks the pore.

bioRxiv · Jul 25, 2024Biochemistry

Mitigation of membrane morphology defects explain stability and orientational specificity of CLC dimers

T. N. Ozturk, N. Bernhardt, N. Schwartz, R. Chadda, J. L. Robertson, J. Faraldo-Gomez

This study shows that CLC-ec1 dimers stabilize by eliminating a membrane defect, using simulations and experiments to support this mechanism.

bioRxiv · Mar 16, 2023 · PreprintBiophysics

Dimerization of a membrane transporter is driven by differential energetics of lipid solvation of dissociated and associated states

R. Chadda, N. Bernhardt, E. G. Kelley, S. C. M. Teixeira, K. Griffith, A. Gil-Ley, T. N. Ozturk, L. E. Hughes, A. Forsythe, V. Krishnamani, J. Faraldo-Gomez, J. L. Robertson

bioRxiv · Oct 5, 2020Biophysics

Hybridization capture of larch (Larix Mill.) chloroplast genomes from sedimentary ancient DNA reveals past changes of Siberian forests

L. Schulte, N. Bernhardt, K. R. Stoof-Leichsenring, H. H. Zimmermann, L. A. Pestryakova, L. S. Epp, U. Herzschuh

This study uses hybridization capture on sedimentary ancient DNA to reconstruct past larch population dynamics in Siberia, revealing an ancient invasion of Larix gmelinii into the range of Larix sibirica.

bioRxiv · Jan 6, 2020Ecology

Genome-wide sequence information reveals recurrent hybridization among diploid wheat wild relatives

N. Bernhardt, J. Brassac, X. Dong, E.-M. Willing, C. H. Poskar, B. Kilian, F. R. Blattner

This study uses genome-wide sequence data to reconstruct the phylogeny of diploid wheat wild relatives and identifies recurrent hybridization events shaping their evolution.

bioRxiv · Jun 21, 2019Evolutionary Biology

Unleashing floret fertility by a mutated homeobox gene improved grain yield during wheat evolution under domestication

S. Sakuma, G. Golan, Z. Guo, T. Ogawa, A. Tagiri, K. Sugimoto, N. Bernhardt, J. Brassac, M. Mascher, G. Hensel, S. Ohnishi, H. Jinno, Y. Yamashita, I. Ayalon, Z. Peleg, , T. Komatsuda

This study identifies GNI1, a homeobox gene whose mutations increased floret fertility and grain yield in wheat during domestication.

bioRxiv · Oct 4, 2018Plant Biology