MicrobiologybioRxivPreprint
Shifting a Cellular Metabolic Landscape Identifies a Refractory Environment for Flavivirus Replication
R. C. Gullberg, N. Chotiwan, M. N. Islam…·R. Perera
The paper identifies a refractory metabolic environment induced by fatty acid biosynthesis inhibition that limits flavivirus replication and shows that combining this with nucleotide synthesis pathway inhibition significantly reduces viral infectivity.
DOI 10.1101/2022.02.21.481365