Pharmacology & ToxicologybioRxiv
Ligand-directed covalent labelling of a GPCR with a fluorescent tag
L. A. Stoddart, N. D. Kindon, O. Otun…·B. Kellam
The paper describes a compound that covalently labels a GPCR with a fluorescent tag without blocking its binding site, enabling study of native GPCR function and localization.
DOI 10.1038/s42003-020-01451-w