Linking modulation of bio-molecular phase behaviour with collective interactions
D. Qian, H. Ausserwoger, W. E. Arter, R. Scrutton, T. J. Welsh, T. Kartanas, N. Ermann, S. Qamar, C. Fischer, T. Sneideris, P. St George-Hyslop, R. V. Pappu, T. Knowles
This paper introduces a dominance analysis framework to determine the molecular mechanism of condensate modulation, demonstrating its application to G3BP1/RNA condensates disrupted by suramin.
bioRxiv · Nov 2, 2023 · PreprintBiophysics