Author

N. Jaeger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

D. T. W. Jones· 2 shared M. Blattner-Johnson· 2 shared S. M. Pfister· 2 shared A. Hernandez-Leyva· 1 shared A. Korshunov· 1 shared A. L. Kau· 1 shared A. L. Rosen· 1 shared A. Rademacher· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

D. T. W. Jones

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell-state plasticity drives heterogeneity in Group 3/4 medulloblastoma

P. Joshi, P. B. G. da Silva, K. Okonechnikov, T. Stelzer, I. Sarropoulos, M. Sepp, J. Nolle, M. V. Pour-Jamnani, A. Rademacher, T. Yamada, C. Schneider, J. Schmidt, L. Bianchini, P. Schaefer, K. Leiss, , L. M. Kutscher

This study identifies cell-state plasticity as a driver of heterogeneity in Group 3/4 medulloblastomas, showing that transcription factor perturbation can redirect tumor cells along different differentiation trajectories.

bioRxiv · Feb 9, 2024 · PreprintCancer Biology

The asthma gut microbiota influences lung inflammation in gnotobiotic mice

N. G. Wilson, A. Hernandez-Leyva, A. L. Rosen, N. Jaeger, R. T. McDonough, J. Santiago-Borges, M. A. Lint, T. R. Rosen, C. P. Tomera, L. B. Bacharier, S. J. Swamidass, A. L. Kau

This study shows that ETBF in the gut microbiota of older asthma patients is linked to increased lung inflammation in gnotobiotic mice.

bioRxiv · Aug 9, 2022Microbiology

Comprehensive analysis of mutational signatures in pediatric cancers

V. Thatikonda, S. M. A. Islam, B. C. Jones, S. N. Groebner, G. Warsow, B. Hutter, D. Huebschmann, S. Froehling, M. Blattner-Johnson, D. T. W. Jones, L. B. Alexandrov, S. M. Pfister, N. Jaeger

This study analyzes mutational signatures in pediatric cancers, finding fewer active signatures compared to adult cancers and linking specific signatures to TP53 mutations and chromothripsis.

bioRxiv · Sep 28, 2021Cancer Biology