Author

V. Thatikonda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

A. A. Machado· 1 shared A. Jeschko· 1 shared A. Sorokin· 1 shared B. C. Jones· 1 shared B. Hutter· 1 shared C. A. Bristow· 1 shared C. P. Vellano· 1 shared D. Gerlach· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. A. Machado

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2 papers

Recent·Most cited

Combined KRASG12C and SOS1 inhibition enhances and extends the anti-tumor response in KRASG12C-driven cancers by addressing intrinsic and acquired resistance

V. Thatikonda, H. Lu, S. Jurado, K. Kostyrko, C. A. Bristow, K. Bosch, N. Feng, S. Gao, D. Gerlach, M. Gerlach, S. Lieb, A. Jeschko, A. A. Machado, E. D. Marszalek, M. Mahendra, , M. H. Hofmann

This study shows that combining KRASG12C and SOS1 inhibitors improves anti-tumor response and delays resistance in KRASG12C-driven cancers.

bioRxiv · Jan 23, 2023Cancer Biology

Comprehensive analysis of mutational signatures in pediatric cancers

V. Thatikonda, S. M. A. Islam, B. C. Jones, S. N. Groebner, G. Warsow, B. Hutter, D. Huebschmann, S. Froehling, M. Blattner-Johnson, D. T. W. Jones, L. B. Alexandrov, S. M. Pfister, N. Jaeger

This study analyzes mutational signatures in pediatric cancers, finding fewer active signatures compared to adult cancers and linking specific signatures to TP53 mutations and chromothripsis.

bioRxiv · Sep 28, 2021Cancer Biology