Author

N. L. Grant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:non-human primate· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. L. Flynn· 3 shared P. L. Lin· 3 shared P. Maiello· 3 shared A. G. White· 2 shared H. J. Borish· 2 shared J. T. Mattila· 2 shared L. J. Frye· 2 shared A. A. Tu· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

J. L. Flynn

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mycobacterium tuberculosis-specific CD4 T cells expressing transcription factors associate with bacterial control in granulomas

N. L. Grant, K. Kelly, P. Maiello, H. Abbott, S. L. O'Connor, P. L. Lin, C. A. Scanga, J. L. Flynn

The paper identifies Mtb-specific CD4 T cells in granulomas and shows that transcription factors T-bet and RORγT correlate with bacterial control.

bioRxiv · Nov 30, 2022 · PreprintImmunology

T cell transcription factor expression evolves as adaptive immunity matures in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques

N. L. Grant, P. Maiello, E. Klein, P. L. Lin, H. J. Borish, J. Tomko, L. J. Frye, A. G. White, D. E. Kirschner, J. T. Mattila, J. L. Flynn

This study tracks T cell transcription factor expression in granulomas of Mtb-infected macaques over time, showing increased T-bet+ T cells correlate with reduced bacterial burden.

bioRxiv · Jan 25, 2022 · PreprintImmunology

Multimodal profiling of lung granulomas reveals cellular correlates of tuberculosis control

H. P. Gideon, T. K. Hughes, C. N. Tzouanas, M. H. Wadsworth, A. A. Tu, T. M. Gierahn, J. M. Peters, F. H. Hopkins, J.-R. Wei, C. Kummerlowe, N. L. Grant, K. Nargan, J. Phuah, H. J. Borish, P. Maiello, , A. K. Shalek

The paper identifies cellular and temporal factors associated with bacterial control in tuberculosis granulomas using multimodal data.

bioRxiv · Oct 24, 2020 · PreprintImmunology