Author

N. Michelarakis

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Biophysics· 1

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Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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C. Aponte-Santamaria· 1 shared F. Gräter· 1 shared R. Roessner· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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1 shared paperBiophysics

C. Aponte-Santamaria

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1 paper

Recent·Most cited

BiophysicsbioRxivJul 31, 2023

Mechanical forces control the valency of the malaria adhesin VAR2CSA by exposing cryptic glycan binding sites

R. Roessner, N. Michelarakis, F. Gräter, C. Aponte-Santamaria

This study shows mechanical forces increase VAR2CSA's binding avidity by converting it from monovalent to multivalent through conformational changes exposing additional CSA binding sites.

DOI 10.1371/journal.pcbi.1011726

humanprotein structure

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