Author

N. Moore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Cheung· 1 shared A. Dixson· 1 shared A. Gray· 1 shared A. Imamovic· 1 shared B. Reardon· 1 shared C. J. Ryan· 1 shared C. M. Russell· 1 shared D. Alves· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. Cheung

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Computational Framework for the Administration of 5-Aminovulinic Acid before Glioblastoma Surgery

J. Zeng, N. Moore

The paper develops a computational framework to simulate 5-ALA transport and fluorescence in glioblastoma patients, showing peak fluorescence occurs 2-7 hours post-administration, consistent with current guidelines.

bioRxiv · Dec 7, 2023Pharmacology & Toxicology

ATOMDANCE: kernel-based denoising and allosteric resonance analysis for functional and evolutionary comparisons of protein dynamics

G. A. Babbitt, M. Rajendran, M. L. Lynch, R. Asare-Bediako, L. T. Mouli, C. J. Ryan, H. Srivastava, P. Rynkiewicz, K. Phadke, M. L. Reed, N. Moore, M. C. Ferran, E. P. Fokoue

ATOMDANCE compares and denoises protein motion dynamics between functional or evolutionary states using kernel-based methods to identify key sites and functional shifts.

bioRxiv · Apr 20, 2023Biophysics

The C. albicans virulence factor Candidalysin polymerizes in solution to form membrane pores and damage epithelial cells.

C. M. Russell, K. Schaefer, A. Dixson, A. Gray, R. J. Pyron, D. Alves, N. Moore, E. Conley, T. White, T. Do, G. King, F. N. Barrera

This study reveals that Candidalysin polymerizes in solution to form membrane pores, damaging epithelial cells, and identifies polymerization as a therapeutic target for candidiasis.

bioRxiv · Nov 11, 2021 · PreprintBiophysics

Clinical interpretation of integrative molecular profiles to guide precision cancer medicine

B. Reardon, N. D. Moore, N. Moore, E. Kofman, S. Aldubayan, A. Cheung, J. Conway, H. Elmarakeby, A. Imamovic, S. C. Kamran, T. Keenan, D. Keliher, D. J. Konieczkowski, D. Liu, K. Mouw, , E. M. Van Allen

This paper introduces MOAlmanac, a clinical interpretation algorithm that integrates genomic and transcriptional data to improve precision cancer treatment decisions by considering second-order molecular features.

bioRxiv · Sep 22, 2020Cancer Biology