MicrobiologybioRxiv
Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes the hexameric complex
D. L. Hurdiss, P. El Kazzi, L. Bauer…·B. Coutard
This study identifies fluoxetine as an inhibitor of the enterovirus 2C AAA+ ATPase, revealing its mechanism of action through structural and functional analyses.
DOI 10.1126/sciadv.abj7615