Author

N. R. Zemke

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Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. Berk· 1 shared E. Hsu· 1 shared J. A. Wohlschlegel· 1 shared J. Sha· 1 shared W. D. Barshop· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

A. J. Berk

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1 paper

Recent·Most cited

MicrobiologybioRxivPreprintDec 16, 2020

Adenovirus E1A Binding to DCAF10 Targets Degradation of AAA+ ATPases Required for Quaternary Assembly of Multiprotein Machines and Innate Immunity

N. R. Zemke, W. D. Barshop, J. Sha…·A. J. Berk

The paper identifies that adenovirus E1A's C-terminal region interacts with host proteins to form a complex that degrades AAA+ ATPases, thereby inhibiting IRF3 stabilization and innate immune responses.

DOI 10.1101/2020.12.16.423151

humanproteomics

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