BiophysicsbioRxiv
Synthesis runs counter to directional folding of a nascent protein domain
X. Chen, N. Rajasekaran, K. Liu, C. M. Kaiser
The paper shows that the G-domain of elongation factor G remains unfolded during synthesis and folds after exiting the ribosome, following a C-to-N terminal folding pathway.
DOI 10.1038/s41467-020-18921-8