N. Ramakrishnan

High fidelity epigenetic inheritance: Information theoretic model predicts k-threshold filling of histone modifications post replication

The paper develops an information-theoretic model to predict how histone modifications are inherited post-replication, showing that enzymes may use a k-threshold filling algorithm to recover parental modifications.

Cell cycle checkpoints cooperate to suppress DNA and RNA associated molecular pattern recognition and anti-tumor immune responses

The paper shows that disrupting cell cycle checkpoints can restore DNA damage-induced inflammation and anti-tumor immune responses in cancer cells.