BiophysicsbioRxiv
Autoinhibition in the Signal Transducer CIN85 Modulates B Cell Activation
D. Sieme, M. Engelke, N. Rezaei-Ghaleh…·C. Griesinger
This study identifies an intramolecular SH3:PRM interaction in CIN85 that modulates its valency and phase separation, affecting B cell activation.
DOI 10.1021/jacs.3c09586