Cell BiologybioRxivPreprint
Extracellular Matrix Stiffness Alters TRPV4 Regulation in Chondrocytes
N. S. Trompeter, C. J. Farino, M. Griffin…·R. L. Duncan
This study shows that softer cartilage substrates reduce TRPV4-mediated calcium influx and increase chondrocyte apoptosis, which can be mitigated by TRPV4 agonism.
DOI 10.1101/2021.09.14.460172