Cancer BiologybioRxiv
Charting the transcriptomic landscape of primary and metastatic cancers in relation to their origin and target normal tissues
N. Sanghvi, C. Calvo-Alcaniz, P. Rajagopal…·N. Nair
The paper compares gene expression in primary and metastatic tumors to their origin and target tissues, finding metastases more resemble target tissues and show reduced cancer hallmark activity.
DOI 10.1126/sciadv.adn0220