Pharmacology & ToxicologybioRxivPreprint
Developmental Manganese Exposure Causes Lasting Attention Deficits Accompanied by Dysregulation of mTOR Signaling and Catecholaminergic Gene Expression in Brain Prefrontal Cortex
DOI 10.1101/2023.07.16.549215
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2 papers
Recent·Most cited
S. Beaudin, S. L. Howard, N. Santiago…·D. R. Smith
This study shows that methylphenidate (MPH) reduces attention and sensorimotor impairments caused by developmental manganese exposure in rats, with varying effective doses and receptor-specific mechanisms.