MicrobiologybioRxiv
Molecular Determinants of Tissue Specificity of Flavivirus Nonstructural Protein 1 Interaction with Endothelial Cells
N. T. Lo, S. Roodsari, N. R. Tin…·E. Harris
This study identifies molecular determinants of flavivirus NS1 that confer tissue-specific endothelial dysfunction and vascular leak, highlighting the role of the wing domain and a three-residue motif.
DOI 10.1128/jvi.00661-22