ImmunologybioRxivPreprint
Endogenous bystander killing mechanisms enhance the activity of novel FAP-CAR-T cells against glioblastoma
W. Yu, N. T. Truong, R. Polara…·M. P. Brown
This study shows FAP-CAR-T cells effectively kill glioblastoma cells through bystander mechanisms, even when only some cells express FAP, and demonstrate therapeutic efficacy in vivo.
DOI 10.1101/2023.02.21.529331