Author

N. Tchitchek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:non-human primate· 3 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

R. Le Grand· 3 shared V. Contreras· 2 shared A. Hubert· 1 shared A. Le Tortorec· 1 shared A. Rolland· 1 shared A.-S. Beignon· 1 shared A.-S. Gallouet· 1 shared B. 't Hart· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersImmunology

R. Le Grand

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Author profile →

5 papers

Recent·Most cited

Tissue-resident uterine regulatory T cells support fetal growth

L. M. Florez, G. Fourcade, G. Darrasse-Jeze, P. Barennes, K. Gan-Fernandez, P. Regnier, D. Nehar-Belaid, T. Courau, M. G. Ruocco, S. Zacchigna, M. Giacca, J. Lion, N. Mooney, N. Tchitchek, E. Mariotti-Ferrandiz, D. Klatzmann

The paper identifies uterine tissue-resident regulatory T cells (uTregs) that support fetal growth by promoting uterine remodeling and vascular development during pregnancy.

bioRxiv · Sep 7, 2023 · PreprintImmunology

The route of vaccine administration determines whether blood neutrophils undergo long-term phenotypic modifications

Y. Feraoun, C. Joly, J.-L. Palgen, N. Tchitchek, E. Marcos-Lopez, N. Dereuddre-Bosquet, A.-S. Gallouet, V. Contreras, Y. Levy, F. Martinon, R. Le Grand, A.-S. Beignon

This study shows that subcutaneous vaccine administration leads to long-term phenotypic changes in blood neutrophils, unlike intradermal administration, highlighting the role of delivery route in immune training.

bioRxiv · Oct 26, 2021Immunology

Human USP18 is regulated by miRNAs via the 3'UTR, a sequence duplicated in lincRNA genes residing in chr22q11.21

E. Rubino, M. Cruciani, N. Tchitchek, A. Le Tortorec, A. Rolland, O. Veli, L. Vallet, G. Gaggi, F. Michel, N. Dejucq-Rainsford, S. Pellegrini

The paper identifies miRNAs that regulate USP18 via its 3'UTR and discovers duplicated 3'UTR sequences in lincRNAs on chr22q11.21, suggesting a regulatory network for baseline USP18 levels.

bioRxiv · Oct 7, 2020Immunology

Targeting MOG to skin macrophages prevents EAE in macaques through TGFβ-induced peripheral tolerance

C.-M. Fovet, L. Stimmer, V. Contreras, P. Horellou, A. Hubert, N. Seddiki, C. Chapon, S. Tricot, C. Leroy, J. Flament, J. Massonneau, N. Tchitchek, B. 't Hart, S. Zurawski, P. Klucar, , C. Serguera

This paper shows that targeting MOG to skin macrophages via a fusion protein prevents EAE in macaques by inducing TGFβ-mediated peripheral tolerance.

bioRxiv · Mar 9, 2019 · PreprintImmunology

Stage-specific ISG expression reveals functional convergence of type I and II IFNs in SIV infection

N. Echebli, N. Tchitchek, S. Dupuy, T. Bruel, C. Pereira Bittencourt Passaes, N. Bosquet, R. Le Grand, C. Bourgeois, B. Favier, R. Cheynier, O. Lambotte, B. Vaslin

The paper analyzes ISG expression in SIV-infected macaques to show that both type-I and type-II IFNs contribute to ISG upregulation, with type-II IFN persisting during chronic infection.

bioRxiv · Sep 22, 2017Immunology