Author

A. Hubert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:DNA methylation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Grinshpun· 2 shared A. Salah· 2 shared A. Zick· 2 shared J. E. Cohen· 2 shared M. Maoz· 2 shared M. Temper· 2 shared T. Peretz· 2 shared A. Blake· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

A. Grinshpun

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Author profile →

5 papers

Recent·Most cited

Enhanced neuroimaging with a calcium sensor in the live adult Drosophila Melanogaster brain using closed-loop adaptive optics light-sheet microscopy

A. Hubert, G. Farkouh, F. Harms, C. Veilly, S. Imperato, M. Mercier, V. Loriette, F. Rouyer, A. Fragola

This paper introduces an adaptive optics light-sheet microscope for live Drosophila brain imaging, improving contrast and enabling faster correction of optical aberrations.

bioRxiv · Jan 6, 2023 · PreprintBiophysics

Subtyping of Small Cell Lung Cancer using plasma cell-free nucleosomes

G. Fialkoff, N. Takahashi, I. Sharkia, J. Gutin, N. Hermoni, R. Kumar, L. Pongor, S. Nichols, L. Sciuto, C. Graham, P. Desai, M. Nirula, P. Suresh, M. Abel, R. Elmeskini, , A. Thomas

This study uses cfChIP-seq on plasma samples to subtype SCLC based on epigenetic states, linking plasma nucleosome data to tumor transcriptomes and developing a classifier for lineage-defining transcription factors.

bioRxiv · Jun 24, 2022 · PreprintCancer Biology

Multiplexed Single-Molecule Epigenetic Analysis of Plasma-Isolated Nucleosomes for Cancer Diagnostics

V. Fedyuk, N. Erez, N. Furth, O. Beresh, D. Jones, A. Shinde, K. Andreishcheva, B. B. Zakai, Y. Mavor, T. Peretz, A. Hubert, J. E. Cohen, A. Salah, M. Temper, A. Grinshpun, , E. Shema

The paper develops EPINUC, a single-molecule assay for analyzing plasma nucleosomes to detect cancer with high accuracy, including early-stage colorectal cancer and determining tumor origin.

bioRxiv · Nov 1, 2021Cancer Biology

TET2 drives 5hmc marking of GATA6 and epigenetically defines pancreatic ductal adenocarcinoma transcriptional subtypes

M. Eyres, S. Lanfredini, A. Burns, A. Blake, F. Willenbrock, R. Goldin, D. Hughes, S. Hughes, A. Thapa, D. Valoulis, A. Hubert, Z. D'Costa, A. Sabbagh, A. G. Abraham, C. Blancher, , E. O'Neill

This study identifies TET2-driven 5hmc loss at GATA6 as a mechanism defining PDAC transcriptional subtypes and shows that TET2 stabilization with Metformin and Vitamin C reverses squamous-like tumor features.

bioRxiv · Oct 22, 2020Cancer Biology

Targeting MOG to skin macrophages prevents EAE in macaques through TGFβ-induced peripheral tolerance

C.-M. Fovet, L. Stimmer, V. Contreras, P. Horellou, A. Hubert, N. Seddiki, C. Chapon, S. Tricot, C. Leroy, J. Flament, J. Massonneau, N. Tchitchek, B. 't Hart, S. Zurawski, P. Klucar, , C. Serguera

This paper shows that targeting MOG to skin macrophages via a fusion protein prevents EAE in macaques by inducing TGFβ-mediated peripheral tolerance.

bioRxiv · Mar 9, 2019 · PreprintImmunology