Author

N. Uma Naresh

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Cell Biology· 1

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Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

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C. Haynes· 1 shared J. Lavelle· 1 shared K. Luk· 1 shared N. Anderson· 1 shared P. Chien· 1 shared P. Liu· 1 shared Q. Yang· 1 shared R. Zeinert· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperCell Biology

C. Haynes

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintSep 1, 2020

mtDNA replication in dysfunctional mitochondria promotes deleterious heteroplasmy via the UPRmt

Q. Yang, P. Liu, N. Anderson…·C. Haynes

The paper shows ATFS-1 promotes {Delta}mtDNA replication by recruiting POLG, while LONP-1 inhibition increases wildtype mtDNA binding and improves heteroplasmy ratio and OXPHOS function.

DOI 10.1101/2020.09.01.274472

C. eleganshuman

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