ZNF524 directly interacts with telomeric DNA and supports telomere integrity
H. Braun, Z. Xu, F. Chang, N. Viceconte, G. Rane, M. Levin, L. Lototska, F. Roth, A. Hillairet, A. Fradera-Sola, V. Khanchandani, O. Dreesen, Y. Yang, Y. Shi, F. Li, , D. Kappei
This study identifies ZNF524 as a telomere-binding protein that maintains telomere integrity by supporting TRF2/RAP1 localization and preventing DNA damage and recombination.
bioRxiv · Nov 30, 2022Cell Biology