F. Butter

Revealing the Arabidopsis AtGRP7 mRNA binding proteome by specific enhanced RNA interactome capture

The paper identifies proteins interacting with the AtGRP7 mRNA in Arabidopsis using enhanced RNA interactome capture, revealing ALBA proteins as binders.

Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes

The paper investigates the dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes, revealing expanded piwil1 genes and divergent piRNA-producing loci.

The protein phosphatase-2A subunit PR130 is linked to cytotoxic protein aggregate formation in mesenchymal pancreatic ductal adenocarcinoma cells

This study shows that mesenchymal pancreatic ductal adenocarcinoma cells depend on the PP2A subunit PR130, and its inhibition by phendione leads to apoptosis and protein aggregate formation.

Distinct clades of TELOMERE REPEAT BINDING transcriptional regulators interplay to regulate plant development

This study identifies TRB4 and TRB5 as distinct TRB clades that regulate plant development through both PRC2-dependent and independent mechanisms, affecting gene expression and developmental responses to environmental cues.

Mitochondrial translation regulates terminal erythroid differentiation by maintaining iron homeostasis

This study shows that Mto1 dysfunction disrupts mitochondrial translation, leading to iron overload and defective erythroid differentiation.

E4F1 and ZNF148 are transcriptional activators of the A57C and wildtype TERT promoter

The paper identifies E4F1 and ZNF148 as transcriptional activators of the A57C and wildtype TERT promoter, respectively, and shows their role in upregulating TERT transcription and telomerase activity.

Long live the host! Proteomic analysis reveals possible strategies for parasitic manipulation of its social host

This study identifies parasite-secreted proteins and host proteome changes in ants infected with Anomotaenia brevis, revealing strategies for host manipulation through antioxidant proteins and altered translational activity.

ZNF524 directly interacts with telomeric DNA and supports telomere integrity

This study identifies ZNF524 as a telomere-binding protein that maintains telomere integrity by supporting TRF2/RAP1 localization and preventing DNA damage and recombination.

The nucleolar DExD/H protein Hel66 is involved in ribosome biogenesis in Trypanosoma brucei

This study identifies Hel66, a DExD/H box helicase, as essential for ribosome biogenesis in Trypanosoma brucei, showing its role in translation and rRNA processing.

A membrane-associated condensate drives paternal epigenetic inheritance in C. elegans

This study identifies a phase separation mechanism involving PEI-1 that enables paternal epigenetic inheritance in C. elegans by securing WAGO-3 in sperm.

The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1

This study identifies TEBP-1 and TEBP-2 as double-stranded telomere-binding proteins in C. elegans that form a complex with POT-1, and shows their distinct roles in telomere length regulation and fertility.

Characterization of two novel proteins involved in mitochondrial DNA anchoring

This study identifies two novel proteins involved in mitochondrial DNA anchoring in Trypanosoma brucei by combining proteomics and RNAi, showing their localization and essential role in kDNA stability.

Characterization of the Novel Mitochondrial Genome Segregation Factor TAP110 in Trypanosoma brucei

This study identifies TAP110 as a novel mitochondrial genome segregation factor in Trypanosoma brucei and shows its proximal positioning to kDNA using ultrastructure expansion microscopy.

Genome maintenance functions of Trypanosoma brucei DNA Polymerase N include telomere association and a role in antigenic variation

This study identifies a dual role for DNA Polymerase N in Trypanosoma brucei, showing its involvement in telomere maintenance and antigenic variation, contributing to genome stability and immune evasion.