BiochemistrybioRxiv
ChIP-MS reveals the local chromatin composition by label-free quantitative proteomics
W. K. Yong, G. Rane, N. Zaal Anuar…·D. Kappei
The paper introduces ChIP-MS, a method combining ChIP with label-free quantitative mass spectrometry to analyze local chromatin composition, demonstrating its application at telomeres, with transcription factors, in tissue, and via dCas9-driven enrichment.
DOI 10.1038/s41467-026-73609-9