MicrobiologybioRxiv
SARS-CoV-2 ORF8 modulates lung inflammation and clinical disease progression
Marisa E. McGrath, Yong Xue, Louis Taylor…·Matthew B. Frieman
This study shows that SARS-CoV-2 ORF8 protein modulates lung inflammation and disease severity in mice by affecting macrophage infiltration and function.
DOI 10.1371/journal.ppat.1011669