Cell BiologyNature MicrobiologyPeer-reviewed
A host AAA-ATPase exhibits bacteriolytic activity for clearance of microbial infection
Sourav Ghosh, Suvapriya Roy, Navin Baid…·Anirban Banerjee
The paper shows that the host AAA-ATPase VCP/p97 has bacteriolytic activity by mechanically extracting ubiquitinated proteins from bacterial membranes, leading to microbial clearance in a mouse sepsis model.
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