NeurosciencebioRxivPreprint
Cav3.1 is a leucine sensor in POMC neurons mediating appetite suppression and weight loss
Anthony H. K. Tsang, Nicholas Heeley, Constanza Alcaino…·Clémence Blouet
2 citations
Author
Nicholas Heeley
University of Cambridge
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2017-2024 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
Recent·Most cited
- NeuroscienceMolecular MetabolismPeer-reviewed
Rapid sensing of L-leucine by human and murine hypothalamic neurons: neurochemical and mechanistic insights
Nicholas Heeley, Peter Kirwan, Tamana Darwish…·Clémence Blouet
This study identifies novel Ca2+ signaling mechanisms by which hypothalamic neurons in mice and humans rapidly respond to L-leucine, showing both activation and inhibition of specific neuron types.
- NeuroscienceMolecular MetabolismPeer-reviewed
Heterogeneity of hypothalamic Pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing
Brian Lam, Irène Cimino, Joseph Polex-Wolf…·Giles S.H. Yeo
The paper uses single-cell RNA sequencing to reveal heterogeneity in murine hypothalamic POMC neurons, identifying distinct subpopulations with different gene expression profiles and receptor expression.