Cancer BiologybioRxivPreprint
Developmental Plasticity and Stromal Co-option Shape a Pituitary Neuroendocrine Tumor Transcriptional Continuum
Robert C. Osorio, Jun Yeop Oh, Ankita Sati…·Manish Kumar Aghi
This study uses snRNA-seq and spatial transcriptomics to show PitNETs exhibit transcriptional continuity and originate from different developmental pathways, influenced by stromal interactions.