Developmental BiologyThe CRISPR JournalPeer-reviewed
Low-density Lipoprotein Receptor-related Protein 5 (LRP5)-deficient Rats Have Reduced Bone Mass and Abnormal Development of the Retinal Vasculature
John L. Ubels, Cassandra R. Diegel, Gabrielle E. Foxa…·Bart O. Williams
This study creates Lrp5-deficient rats using CRISPR/Cas9, showing reduced bone mass and abnormal retinal vasculature similar to human LRP5 deficiency.
16 citations