Author

O. Begik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

E. M. Novoa· 3 shared A. Delgado-Tejedor· 2 shared R. Medina· 2 shared A. Heit-Mondrzyk· 1 shared B. Baquero-Perez· 1 shared C. B. Vagbo· 1 shared C. Baldus· 1 shared C. Mueller-Tidow· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMicrobiology

E. M. Novoa

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Unbiased functional genetic screens reveal essential RNA modifications in human cancer and drug resistance

C. Pauli, M. Kienhoefer, M. Blank, O. Begik, C. Rohde, D. Heid, F. Xu, S. M. N. Zimmermann, K. Weidenauer, S. Delaunay, N. Krall, K. Trunk, D. Zhao, F. Zhou, A. Heit-Mondrzyk, , M. Frye

The paper identifies essential RNA modifications in cancer using CRISPR screens and finds that mitochondrial metabolic plasticity influences drug resistance through specific RNA modifications.

bioRxiv · Jul 13, 2024 · PreprintCell Biology

N6-methyladenosine modification is not a general trait of viral RNA genomes

B. Baquero-Perez, I. D. Yonchev, A. Delgado-Tejedor, R. Medina, M. Puig-Torrents, I. M. Sudbery, O. Begik, S. A. Wilson, E. M. Novoa, J. Diez

The paper investigates m6A modification in viral RNA genomes and finds no evidence of m6A in CHIKV or DENV transcripts using multiple orthogonal methods.

bioRxiv · Oct 13, 2023Microbiology

Native RNA nanopore sequencing reveals antibiotic-induced loss of rRNA modifications in the A- and P-sites

A. Delgado-Tejedor, R. Medina, O. Begik, L. Cozzuto, J. Ponomarenko, E. M. Novoa

This study uses native RNA nanopore sequencing to show antibiotic-induced loss of rRNA modifications in the A- and P-sites, revealing their role in antibiotic resistance.

bioRxiv · Mar 21, 2023Microbiology