Author

O. Gielen

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Graux· 1 shared D. Dierickx· 1 shared D. Nittner· 1 shared J. Cools· 1 shared K. Debackere· 1 shared K. Jacobs· 1 shared K. Kataoka· 1 shared M. Vanden Bempt· 1 shared

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2022-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

C. Graux

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1 paper

Recent·Most cited

Cancer BiologybioRxivMar 31, 2022

Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T cell lymphoma

M. Vanden Bempt, K. Debackere, S. Demeyer…·D. Dierickx

The paper identifies MYCN overexpression in PTCL and shows EZH2 as a transcriptional co-factor for MYCN-driven gene activation, with therapeutic implications for HDAC inhibitors.

DOI 10.1182/blood.2022016428

humanmouse

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