BiochemistrybioRxiv
Biosynthesis of an Anti-Addiction Agent from the Iboga Plant
S. E. O'Connor, S. Farrow, O. M. Kamileen…·C. Stephenson
The paper reports the biosynthesis of (-)-voacangine and its conversion to (-)-ibogaine, revealing enantioselectivity in enzymatic Diels-Alder reactions for anti-addiction alkaloids.
DOI 10.1021/jacs.9b05999