Multiplexed triage of candidate biomarkers in plasma using internal standard triggered-parallel reaction monitoring mass spectrometry
J. J. Kennedy, J. R. Whiteaker, R. G. Ivey, A. Burian, S. Chowdhury, C.-F. Tsai, T. Liu, C. Lin, O. Murillo, R. A. Lundeen, L. A. Jones, P. R. Gafken, G. Longton, K. D. Rodland, S. Skates, , A. G. Paulovich
This paper introduces an IS-PRM assay to prioritize plasma biomarkers for validation, showing improved sensitivity and precision over traditional methods.
bioRxiv · Sep 2, 2021 · PreprintCancer Biology