C.-F. Tsai

Computational ranking-assisted identification of Plexin-B2 in homotypic and heterotypic clustering of circulating tumor cells in breast cancer metastasis

This study identifies Plexin-B2 as a driver of homotypic and heterotypic CTC clusters in breast cancer metastasis, with high expression linked to poor prognosis and therapeutic potential.

Phosphorylation barcodes direct biased chemokine signaling at CXCR3

The paper shows that CXCR3 chemokines use different phosphorylation barcodes to activate distinct signaling pathways, leading to varied physiological outcomes.

A Suspension Trapping-Based Sample Preparation Workflow for Sensitive Plant Phosphoproteomics

The paper develops a tandem S-Trap-IMAC method for plant phosphoproteomics, improving coverage and quantification accuracy in Arabidopsis.

A streamlined tandem tip-based workflow for sensitive nanoscale phosphoproteomics

This paper introduces a streamlined phosphoproteomics workflow that reduces sample loss and processing time, enabling sensitive detection of phosphopeptides from nanoscale samples.

CD81 partners with CD44 in promoting exosome biogenesis, tumor cluster formation, and lung metastasis in triple negative breast cancer

Proteomic Dissection of a Giant Cell

The paper quantifies polarized protein localization in Stentor coeruleus by cutting cells along the anterior-posterior axis and analyzing proteomic enrichment, finding 30% of proteins show polarized localization.

Multiplexed triage of candidate biomarkers in plasma using internal standard triggered-parallel reaction monitoring mass spectrometry

This paper introduces an IS-PRM assay to prioritize plasma biomarkers for validation, showing improved sensitivity and precision over traditional methods.