Author

O. Rolfson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pathology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:CITE-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. D. Jay· 3 shared K. A. Thomsson· 3 shared N. G. Karlsson· 3 shared R. Krawetz· 3 shared S. Huang· 3 shared T. Eisler· 3 shared A. Struglics· 2 shared C. Jin· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPathology

G. D. Jay

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Multiomic single-cell analysis identifies von Willebrand factor and TIM3-expressing BCR-ABL1+ CML stem cells

M. S. Nilsson, H. Komic, J. Gustafsson, Z. Sheybani, S. Paul, O. Rolfson, K. Hellstrand, L. Wennström, A. Martner, F. B. Thoren

This study identifies VWF and TIM3-expressing BCR-ABL1+ CML stem cells using multiomic single-cell analysis, suggesting they are targets for sustained LSC elimination.

bioRxiv · Sep 14, 2023 · PreprintCancer Biology

The level of synovial human VEGFA, IL-8 and MIP-1α correlate with truncation of lubricin glycans in osteoarthritis

S. Huang, K. A. Thomsson, C. Jin, H. Ryberg, N. Das, A. Struglics, O. Rolfson, L. I. Björkman, T. Eisler, T. A. Schimdt, G. D. Jay, R. Krawetz, N. G. Karlsson

This study finds that synovial levels of IL-8, MIP-1α, and VEGFA correlate with lubricin glycan truncation in OA, suggesting a link between glycan changes and local inflammation.

bioRxiv · Mar 11, 2021 · PreprintPathology

Core-2 O-glycans are required for Galectin-3 interaction with the osteoarthritis related protein lubricin

S. A. Flowers, K. A. Thomsson, L. Ali, S. Huang, Y. Mthembu, S. C. Regmi, J. Holgersson, T. A. Schimdt, O. Rolfson, L. I. Bjorkman, M. Sundqvist, A. Karlsson, G. D. Jay, T. Eisler, R. Krawetz, N. G. Karlsson

The paper shows that core-2 O-glycans are necessary for galectin-3 to bind lubricin, and this interaction is reduced in late-stage osteoarthritis.

bioRxiv · Dec 20, 2019Biochemistry

Cathepsin G Degrades Synovial Fluid Lubricin: Relevance For Osteoarthritis Pathogenesis

S. Huang, K. A. Thomsson, C. Jin, S. Alweddi, A. Struglics, O. Rolfson, L. I. Bjorkman, S. Kalamajsk, T. A. Schmidt, G. D. Jay, R. Krawetz, N. G. Karlsson, T. Eisler

This study shows that cathepsin G degrades lubricin in synovial fluid, contributing to osteoarthritis pathogenesis by reducing joint lubrication.

bioRxiv · Oct 15, 2019 · PreprintPathology