ImmunologybioRxivPreprint
SHORT-TERM CALORIC RESTRICTION IN MICE PROMOTES RESOLUTION OF ATHEROSCLEROSIS, WHILE WEIGHT REGAIN ACCELERATES ITS PROGRESSION
B. Scolaro, E. J. Brown, F. Krautter…·E. Fisher
This study shows that short-term caloric restriction in mice reduces atherosclerosis by promoting Fcgr4+ macrophages, while weight regain accelerates plaque progression by eliminating these cells and reprogramming immune progenitors.