Pharmacology & ToxicologybioRxivPreprint
Key phosphorylation sites for robust β-arrestin2 binding at the mu-opioid receptor revisited
O. Underwood, S. Frizwanker, J. Glenn…·M. Canals
The paper investigates the role of GRK subfamilies in phosphorylation of the MOR C-tail and their impact on β-arrestin2 recruitment, showing GRK2/3 and GRK5/6 have distinct contributions.
DOI 10.1101/2023.12.05.570073