Author

Olga Shestova

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Carl H. June· 1 shared Charly R. Good· 1 shared Elena J. Orlando· 1 shared Karen Thudium Mueller· 1 shared Katharina E. HayeriD· 1 shared Marco RuellaiD· 1 shared Matthew D. WeitzmaniD· 1 shared Nathan Singh· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Carl H. June

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintMay 5, 2019

Impaired tumor death receptor signaling drives resistance to CAR T cell therapy

Nathan Singh, Olga Shestova, Pranali Ravikumar…·Marco Ruella

This study identifies impaired death receptor signaling as a driver of resistance to CAR T cell therapy in B-cell leukemia by showing its role in tumor survival and T cell dysfunction.

DOI 10.1101/627562

mousehuman

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