ImmunologybioRxivPreprint
The type I IFN-IL-27 axis promotes mRNA vaccine-induced CD8+ T cell responses
Anthony T. Phan, Emily Aunins, Elisa Cruz-Morales…·Christopher A. Hunter
This study shows that IL-27, induced by mRNA-LNP vaccines, enhances CD8+ T cell responses through type I IFN signaling, improving vaccine efficacy against pathogens and tumors.
4 citations