BiochemistrybioRxivPreprint
Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry
N. Bai, Y. Adeshina, I. Bychkov…·J. Karanicolas
This paper designs inhibitors for Musashi proteins MSI1 and MSI2 by mimicking hotspot pharmacophores from protein-RNA complexes, showing specificity and activity in multiple assays.
DOI 10.1101/2023.01.09.523326