Author

P. Chatzikyriakou

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

A. K. Gandhi· 1 shared A. Smith· 1 shared B. Usukhbayar· 1 shared C.-X. Song· 1 shared D. R. Silveira· 1 shared L. Quek· 1 shared M. Hasan· 1 shared M. Metzner· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. K. Gandhi

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintAug 24, 2023

Dysregulation of chromatin via H3K27 methylation underpins differentiation arrest in Isocitrate dehydrogenase-mutant Acute Myeloid Leukaemia.

D. R. Silveira, P. Chatzikyriakou, P. Casares Alaez…·L. Quek

This study shows that IDH2 mutations in AML block differentiation by altering H3K27 methylation, and that Enasidenib can reverse this block by modulating chromatin states.

DOI 10.1101/2023.08.24.554641

humanscRNA-seq

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