Author

P. Coffer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

B. Vastert· 2 shared J. van Loosdregt· 2 shared A. Boltjes· 1 shared C. Gulersonmez· 1 shared E. Mocholi· 1 shared E. Stigter· 1 shared F. van Wijk· 1 shared J. Peeters· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

B. Vastert

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Author profile →

2 papers

Recent·Most cited

Glycolytic reprogramming shapes the epigenetic landscape of activated CD4+ T Cells in Juvenile Idiopathic Arthritis

E. Mocholi, T. Chalkiadakis, C. Gulersonmez, E. Stigter, B. Vastert, J. van Loosdregt, S. Prekovic, P. Coffer

This study shows that glycolytic reprogramming in JIA CD4+ T cells drives epigenetic changes linked to inflammation, with potential therapeutic implications.

bioRxiv · Feb 14, 2024 · PreprintImmunology

Epigenetic changes in autoimmune monocytes contribute to disease and can be targeted by JAKinhibition

J. van Loosdregt, J. Peeters, A. Boltjes, R. Scholman, S. Vervoort, P. Coffer, M. Mokry, B. Vastert, F. van Wijk

The paper investigates epigenetic changes in monocytes from JIA patients and shows JAK inhibition can reverse disease-related gene expression.

bioRxiv · Nov 20, 2021 · PreprintImmunology