Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
L. Lutter, M. M. van der Wal, E. C. Brand…·F. van Wijk
This study identifies functional heterogeneity in human regulatory T-cells within inflamed arthritic joints using single-cell sequencing and flow cytometry.
A. Boltjes, A. A. K. Samat, M. Plantinga…·F. van Wijk
This study identifies functional specialization of dendritic cell subsets in synovial fluid of JIA patients, showing cDC2 and monocytes are pro-inflammatory while cDC1 remains quiescent.
J. van Loosdregt, J. Peeters, A. Boltjes…·F. van Wijk
The paper investigates epigenetic changes in monocytes from JIA patients and shows JAK inhibition can reverse disease-related gene expression.
D. M. W. Zaiss, F. Macdonald, J. van Loosdregt
The paper shows that HB-EGF expressed by CD4 T cells prevents Th17 differentiation and autoimmune disease by sustaining IL-2 expression.
G. Mijnheer, L. Lutter, M. Mokry…·F. van Wijk
The paper identifies a conserved human effector Treg signature through transcriptomic and epigenetic analysis, showing overlap with tumor-infiltrating Treg and environment-driven adaptations.
P. J. Hooikaas, H. G. J. Damstra, O. J. Gros…·A. Akhmanova
This study shows that KIF21B limits microtubule growth to enable rapid centrosome polarization in T cells by inducing microtubule pausing and catastrophe.