Structures of AT8 and PHF1 Phospho-Mimetic Tau: Insights Into the Posttranslational Modification Code of Tau Amyloid Formation
N. M. El Mammeri, A. J. Dregni, P. Duan, M. Hong
This study reports the atomic structures of phospho-mimetic tau fibrils, showing how specific phosphorylations lead to distinct aggregate formations.
bioRxiv · Sep 4, 2023 · PreprintBiophysics