M. Hong

Nucleolar stress induced the formation of a nucleolar stress body via the NOSR-1/NUMR-1 axis in Caenorhabditis elegans

The paper identifies a new subnuclear organelle called the nucleolar stress body (NoSB) in C. elegans, formed through the NOSR-1/NUMR-1 axis in response to nucleolar stress.

Preclinical Characterization of the Omicron XBB.1.5-Adapted BNT162b2 COVID-19 Vaccine

The monovalent Omicron XBB.1.5-adapted BNT162b2 mRNA vaccine elicits stronger neutralizing antibody responses against XBB.1.5 and related sublineages than the bivalent Wild Type + Omicron BA.4/5 vaccine.

N-acetylcysteine Microparticles Reduce Cisplatin-induced RSC96 Schwann Cell Toxicity

This paper investigates the protective effect of N-acetylcysteine microparticles against cisplatin-induced toxicity in Schwann cells, showing improved cell viability.

Structures of AT8 and PHF1 Phospho-Mimetic Tau: Insights Into the Posttranslational Modification Code of Tau Amyloid Formation

This study reports the atomic structures of phospho-mimetic tau fibrils, showing how specific phosphorylations lead to distinct aggregate formations.

Altering the substitution and crosslinking of glucuronoarabinoxylans affects cell wall porosity and assembly in Brachypodium distachyon.

This study shows that altering xylan biosynthesis in Brachypodium distachyon affects cell wall porosity and structure, impacting digestibility and biomass properties.

Xylazine co-self-administration suppresses fentanyl consumption during self-administration and induces a unique sex-specific withdrawal syndrome that is not altered by naloxone in rats

This study shows that xylazine reduces fentanyl self-administration in rats and causes sex-specific withdrawal symptoms not affected by naloxone.

Engineering precise adenine base editor with infinitesimal rates of bystander mutations and off-target editing

This paper engineers a precise adenine base editor, ABE9, with reduced bystander mutations and off-target effects, enabling efficient and accurate A-to-G editing in mouse and rat embryos.

Transient Water Wires Mediate Selective Proton Conduction in Designed Channel Proteins

The paper designs proton-conducting channels that use transient water wires to achieve high selectivity for protons over sodium ions.

Discovery of putative Golgi S-Adenosyl methionine transporters reveals the importance of plant cell wall polysaccharide methylation

This study identifies putative Golgi SAM transporters in Arabidopsis and shows their role in cell wall polysaccharide methylation and plant growth.

Neuropilin-1 Mediates SARS-CoV-2 Infection in Bone Marrow-derived Macrophages

This study shows SARS-CoV-2 infects bone marrow-derived macrophages via neuropilin-1, not ACE2, and affects osteoclast function.

Optimizing high-yield production of SARS-CoV-2 soluble spike trimers for serology assays

This study improves the yield of SARS-CoV-2 spike protein for serology assays by optimizing expression and purification parameters, achieving 5 mg/L production.

Pulsed Third-Spin-Assisted Recoupling NMR for Obtaining Long-Range 13C-13C and 15N-13C Distance Restraints

This paper introduces new NMR techniques to measure long-range 13C-13C and 15N-13C distance restraints for protein structure determination.

Extracellular DNA controls expression of Pseudomonas aeruginosa genes involved in nutrient utilization, metal homeostasis, acid pH tolerance, and virulence.

This study identifies eDNA-regulated genes in P. aeruginosa affecting nutrient utilization, metal homeostasis, acid tolerance, and virulence using RNA-seq and functional assays.

The molecular structure of plant sporopollenin

This study determines the molecular structure of pine sporopollenin using thioacidolysis and solid-state NMR, revealing its composition and crosslinking mechanism.