Pharmacology & ToxicologybioRxivPreprint
Selective inhibition of PfATP6 by artemisinins and identification of new classes of inhibitors after expression in yeast
C. M. Moore, J. Wang, Q. Lin…·S. Krishna
The paper develops a yeast-based screening tool to identify PfATP6 inhibitors, confirming artemisinins target PfATP6 and discovering new inhibitor classes.
DOI 10.1101/2021.10.27.466210