Sub physiological temperature induces pervasive alternative splicing in Chinese hamster ovary cells
I. Tzani, C. Monger, K. Motheramgari, C. Gallagher, R. Hagan, P. Kelly, A. Costello, J. Meiller, P. Floris, L. Zhang, M. Clynes, J. Bones, N. Barron, C. Clarke
This study shows that reducing temperature induces widespread alternative splicing in CHO cells, with many events occurring in genes not detected by standard expression analysis.
bioRxiv · Dec 3, 2019Cell Biology